"A significant number of subjects (68.4%) were taking less than half of the recommended daily allowance of proteins and faced problems like hair fall, acne, pigmentation, vitiligo, hirsutism, melasma, and premature aging. "
Garg, S., & Sangwan, A. (2019). Dietary Protein Deficit and Deregulated Autophagy: A New Clinico-diagnostic Perspective in Pathogenesis of Early Aging, Skin, and Hair Disorders. Indian dermatology online journal, 10(2), 115–124. https://doi.org/10.4103/idoj.IDOJ_123_18
Cysteine (an amino acid) insufficiency may contribute to acne by reducing the body's ability to produce glutathione (see https://discord.com/channels/1169738819688468501/1269559943321620580), an important antioxidant that helps combat oxidative stress and inflammation in the skin. This deficiency could lead to increased vulnerability to acne-causing factors, while supplementation with cysteine or precursor NAC may help restore balance and improve skin health in some individuals. #deleted-channel(edited)
Impaired metabolism of branched-chain amino acids and tryptophan
"Serum levels of the branched chain amino acids leucine, isoleucine and valine were significantly higher in the cicatricial acne group (p: <0.001, 0.001, <0.001, respectively) and in the non-cicatricial acne group (p: 0.039, 0.045, 0.001, respectively) compared to healthy subjects. There were also significant positive correlations between the levels of these amino acids and global acne scores (p = 0.048, r = 0.255, p = 0.006, r = 0.354, p = 0.017, r = 0.307, respectively) and scar scores (p = 0.032, r = 0.392, p = 0.021, r = 0.424, p = 0.018, r = 0.427, respectively). Serum tryptophan levels were significantly lower in both scatricial and non-scatricial acne groups compared to healthy subjects (p = 0.033 and < 0.001, respectively)."
"In summary, our study suggests that the metabolic pathway of branched-chain amino acids and other amino acids such as tryptophan and glutamine may play a role in acne pathogenesis and acne scarring."
Balik, Z. B., & Akoglu, G. (2023). Relationship between serum amino acid levels and acne severity. Journal of Radiation Research and Applied Sciences, 16(4), 100714.(edited)
Chipchanged the channel name: Consumption - Protein Insufficiency7/08/2024 9:39 AM
